770.416.9995
GET DIRECTIONS
SCHEDULE NOW

Regenexx® Published Peer-Reviewed Research

Explore the peer-reviewed medical literature and real-world patient data that form the foundation of the Regenexx protocol. This research directly informs how Regenexx treatments are delivered and refined. We invite you to review this evidence to understand the science behind our approach and to help guide your questions during your consultation.
Call 770.416.9995
Learn about Regenexx

Non-surgical treatment of anterior cruciate ligament tears with percutaneous bone marrow concentrate and platelet products versus exercise therapy: a randomized-controlled, crossover trial with 2-year follow-up

Springer Nature, 2025

Establishing metrics of clinically meaningful change for treating knee osteoarthritis with a combination of autologous orthobiologics

Nature, 2025

Intradiscal Injections of Bone Marrow Concentrate or Leukocyte-Rich Platelet-Rich Plasma for the Treatment of Cervical Discogenic Pain: A Case Series

Cureus, 2025

Evidence-Based Clinical Practice Guidelines on Regenerative Medicine Treatment for Chronic Pain: A Consensus Report from a Multispecialty Working Group

Dovepress, 2024

Percutaneous bone marrow concentrate and platelet products versus exercise therapy for the treatment of rotator cuff tears: a randomized controlled, crossover trial with 2-year follow-up

BMC Musculoskelet Disord, 2024

The rate of venous thromboembolism after knee bone marrow concentrate procedures: should we anticoagulate?

International Orthopaedics, 2022

Image-Guided Injection of Anterior Cruciate Ligament Tears With Autologous Bone Marrow Concentrate and Platelets: Midterm Analysis From a Randomized Controlled Trial

Biologic Orthopedic Journal, 2022

Percutaneous autologous bone marrow concentrate for knee osteoarthritis: patient-reported outcomes and progenitor cell content

International Orthopaedics, 2022

Use of Bone Marrow Concentrate to Treat Pain and Musculoskeletal Disorders: An Academic Delphi Investigation

Pain Physician, 2021

Regarding “Intra-articular Mesenchymal Stromal Cell Injections Are No Different From Placebo in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-analysis of Randomized Controlled Trials”

The Journal of Arthroscopy and Related Surgery, 2021

Colony Forming Potential and Protein Composition of Commercial Umbilical Cord Allograft Products in Comparison With Autologous Orthobiologics

The American Journal of Sports Medicine, 2021

Regenerative Injection Treatments Utilizing Platelet Products and Prolotherapy for Cervical Spine Pain: A Functional Spinal Unit Approach

Cureus, 2021

The Treatment of Bone Marrow Lesions Associated with Advanced Knee Osteoarthritis: Comparing Intraosseous and Intraarticular Injections with Bone Marrow Concentrate and Platelet Products

Pain Physician, 2021

Bone Marrow Concentrate (BMC) Therapy in Musculoskeletal Disorders: Evidence-Based Policy Position Statement of American Society of Interventional Pain Physicians (ASIPP)

Pain Physician Journal, 2020

Cryopreserved bone marrow aspirate concentrate as a cell source for the colony-forming unit fibroblast assay

Cytotherapy, 2020

Past, Current and Future Interventional Orthobiologics Techniques and How They Relate to Regenerative Rehabilitation: A Clinical Commentary

The International Journal of Sports Physical Therapy, 2020

A Randomized Controlled Trial of the Treatment of Rotator Cuff Tears with Bone Marrow Concentrate and Platelet Products Compared to Exercise Therapy: A Midterm Analysis

Stem Cells International, 2020

Quantitation of progenitor cell populations and growth factors after bone marrow aspirate concentration

Journal of Translational Medicine, 2019

Platelet lysates from aged donors promote human tenocyte proliferation and migration in a concentrationdependent manner

Bone & Joint Research, 2019

Efficacy of Autologous Bone Marrow Concentrate for Knee Osteoarthritis with and without Adipose Graft

BioMed Research International, 2019

Symptomatic anterior cruciate ligament tears treated with percutaneous injection of autologous bone marrow concentrate and platelet products: a non-controlled registry study

Journal of Translational Medicine, 2018

A specific protocol of autologous bone marrow concentrate and platelet products versus exercise therapy for symptomatic knee osteoarthritis; a randomized control trial with 2 year follow-up

Journal of Translational Medicine, 2018

A New Atlanto-Occipital (C0-C1) Joint Injection Technique

Pain Medicine, 2017

Treatment of lumbar degenerative disc disease-associated radicular pain with culture-expanded autologous mesenchymal stem cells: a pilot study on safety and efficacy

Journal of Translational Medicine, 2017

The use of lumbar epidural injection of platelet lysate for treatment of radicular pain

Journal of Translational Medicine, 2017

Interventional Orthopedics in Pain Medicine Practice

Techniques in Regional Anesthesia and Pain Management, 2016

A multi-center analysis of adverse events among two thousand, three hundred and seventy two adult patients undergoing adult autologous stem cell therapy for orthopaedic conditions

International Orthopaedics, 2016

Intra-discal injection of autologous, hypoxic cultured bone marrow-derived mesenchymal stem cells in five patients with chronic lower back pain: a long-term safety and feasibility study

Journal of Translational Medicine, 2016

Performing a Better Bone Marrow Aspiration

Physical Medicine and Rehabilitation Clinics of North America, 2016

A Dose Response Analysis of a Specific Bone Marrow Concentrate Treatment Protocol for Knee Osteoarthritis

DMC Musculoskeletal Disorders, 2015

Anterior Cruciate Ligament (ACL) Tears treated with Percutaneous Injection of Autologous Bone Marrow Nucleated Cells: A Case Series

Journal of Pain Research, 2015

A Prospective Multi-site Registry Study of a Specific Protocol of Autologous Bone Marrow Concentrate for the Treatment of Shoulder Rotator Cuff Tears and Osteoarthritis

Journal of Pain Research, 2015

Amide-Type Local Anesthetics and Human Mesenchymal Stem Cells: Clinical Implications for Stem Cell Therapy

Stem Cells Transl Med, 2014

Clinical challenges and opportunities of mesenchymal stem cells in musculoskeletal medicine

Stem Cells Transl Med, 2014

Efficacy and Safety of Bone Marrow Concentrate for Osteoarthritis of the Hip; Treatment Registry Results for 196 Patients

Stem Cell Research and Therapy, 2014

Efficacy of autologous bone marrow concentrate for knee osteoarthritis with and without adipose graft

BioMed Research International, 2014

Percutaneous injection of autologous, culture-expanded mesenchymal stem cells into carpometacarpal hand joints: a case series with an untreated comparison group

Wien Med Wochenschr, 2013

A Case Series of Percutaneous Treatment of Non-Union Fractures with Autologous, Culture Expanded, Bone Marrow Derived, Mesenchymal Stem Cells and Platelet Lysate

Journal of Bioengineering and Biomedical Science, 2011

Safety and Complications Reporting Update on the Re-implantation of Culture-Expanded Mesenchymal Stem Cells using Autologous Platelet Lysate Technique

Curr Stem Cell Res Ther, 2011

Osteoblastic differentiation of human and equine adult bone marrow-derived mesenchymal stem cells when BMP-2 or BMP-7 homodimer genetic modification is compared to BMP-2/7 heterodimer genetic modification in the presence and absence of dexamethasone

J Orthop Res, 2010

Safety and complications reporting on the re-implantation of culture-expanded mesenchymal stem cells using autologous platelet lysate technique

Curr Stem Cell Res Ther, 2010

Increased knee cartilage volume in degenerative joint disease using percutaneously implanted, autologous mesenchymal stem cells

Regenerative Sciences Inc, 2008

Regeneration of meniscus cartilage in a knee treated with percutaneously implanted autologous mesenchymal stem cells

Med Hypotheses, 2008

Partial regeneration of the human hip via autologous bone marrow nucleated cell transfer: A case study

Pain Physician, 2006

Explore Regenexx® at Atlanta Innovative Medicine

Ready to see how these research-based protocols apply to your specific condition? Visit our main Regenexx page to learn more about our non-surgical approach, view the full list of treatable injuries, and find out if you are a candidate for interventional orthopedics.
Learn More About Regenexx at AIM


Wait! Don’t leave without your FREE Guide.

A Closer Look at Regenerative Medicine: Comparing Your Options, you'll learn about treatments like Platelet Rich Plasma (PRP), Prolotherapy, Prolozone Therapy, and Stem Cell Therapy. Plus, you'll get treatment comparisons, links to related studies, and more.

Don’t Walk Away—
Rise to the Occasion!

Before you leave, subscribe to our newsletter to get the ED Therapy Comparison Guide! Explore all your options and discover the best ED treatment for you.

Spoiler Alert: AIM’s innovative, natural treatments might be the spontaneity-restoring, spark-flying solution you’ve been searching for!

Pin It on Pinterest

Atlanta Innovative Medicine
Powered by  GDPR Cookie Compliance
Privacy Overview

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.