Treating ED with PRP: Study Highlights Importance of P-Shot®

A recent study published in The Journal of Urology indicates that without the proper methodology, PRP may have low efficacy rates for treating ED, underscoring the importance of following today’s best in class procedure: the P-Shot® protocol—a very specific and carefully developed method for preparing and administering PRP to treat ED. The study, which did not employ the P-Shot® protocol, demonstrated that PRP injections were no more effective than placebo for treating ED. 

In response to this study, Charles Runels, MD, who developed the P-Shot® (or Priapus Shot®), explains that “One of the legitimate criticisms of all of the review articles regarding PRP therapies in every field is that there is a significant variability in what people call PRP. The P-Shot® represents a very specific protocol in the methods of preparing PRP, activating PRP, and injecting the PRP—all of which differ significantly from what was done in Ledesma’s study and which could account for their lack of results.” 

The method of treatment used in this study deviated from the P-Shot® protocol in several ways:

• The method involved an injection technique that limited the amount of penile tissue exposed to treatment.
• The centrifuge used to create the PRP concentrate is not on the FDA-approved list of devices. This technology is important as it is largely responsible for the number of platelets present in the PRP (and as a result, for the PRP’s regenerative capacity). 
• Only 5 cc of PRP was injected into the penile tissue, whereas the P-Shot® procedure involves 10 cc or more. 
• The PRP was not activated prior to injection, as it is with the P-Shot® protocol, resulting in limited growth factors.